Paracetamol Risks- funded by the British Heart Foundation

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Paracetamol could increase blood pressure. Regular use of paracetamol has been linked to higher blood pressure, according to research funded by the British Heart Foundation and published (2022) in the journal Circulation.
The study found that long-term use of paracetamol could increase the risk of heart disease and strokes in people with high blood pressure. Those who had taken the medication for at least six months were found to have a 9% higher risk of developing high blood pressure
compared to those who did not take the painkiller. Researchers from the University of Edinburgh advise that patients with a long-term prescription for the medication should use the lowest effective dose for the shortest possible time.
While paracetamol is generally considered safe for short term use and when used appropriately, regular and long-term use of the medication can have adverse effects.
These include higher blood pressure, liver damage. The findings highlight the importance of monitoring blood pressure in those taking paracetamol regularly and considering alternative and/or non-drug pain relief options where appropriate.
Circulation. 2022;145:416-423
Stroke. 2016;47:1045-1052
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